Canvax Releases New Inorganic Pyrophosphate

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In the Lab eNewsletter, Pharmaceutical Technology's In the Lab eNewsletter, September 2022, Volume 17, Issue 9

Canvax’s new inorganic pyrophosphate is designed for in-vitro transcription reactions.

Canvax, a European supplier of enzymes, recombinant proteins, and similar products, announced the release of a new inorganic pyrophosphate on Aug. 25, 2022. The new enzyme, isolated from E. coli, is a DNA replication enhancer with ≥ 95% purity and has an enhanced capacity for increasing RNA yield in in-vitro transcription (IVT) reactions.

The enzyme has been stable under temperatures below 80º and is free of endonucleases, exonucleases, and RNAses. According to a company press release, this makes it ideal for use in RNA IVT reactions because it can reduce the inhibitory effects of protein-protein interactions. The company also stated in the release that it is suitable for messenger RNA-based vaccine manufacturing, RNA labeling, and enhancement of DNA replication.

“We're glad to contribute with this new launch, significantly to supporting mRNA vaccines manufacturing, and we're pleased that the research community has embraced our pyrophosphatase and our RNA enzymes portfolio,” said Jesus C. Morales, business development manager, Canvax, in the release.


Source: Canvax