Danish Companies and University Collaborate on MRSA Vaccine
Barvarian Nordic, Evaxion Biotech, and the Technical University of Denmark announced plans to collaborate on the development of a vaccine for MRSA.
Bavarian Nordic and Evaxion Biotech, Danish biotechnology companies, and the Technical University of Denmark (DTU) have entered a collaboration for the development of an Modified Vaccinia Ankara - Bavarian Nordic (MVA-BN)-based vaccine against Methicillin-resistant Staphylococcus aureus (MRSA) using Evaxion’s computer-based technology to discover novel antigens. According to a press release from Bavarian Nordic, the same approach could potentially be used to target any other bacteria that have developed resistance to antibiotics.
Based on efficacy results demonstrated by Evaxion in preclinical models, Bavarian Nordic intends to engineer and produce a MVA-BN-based vaccine candidate, which will be investigated in additional preclinical studies by DTU. If proven safe and efficacious, human trials could occur in 2019.
The project received initial funding from the Innovation Fund Denmark in the amount of Danish Krone (DKK) 17 million (USD 2.5 million), which in part will fund Bavarian Nordic’s production of MVA-BN-based MRSA vaccine candidates.
MRSA is associated with deaths and a high rate of hospitalization. MRSA remains a major challenge in the healthcare sector due to high infection risk during treatment and surgery of patients, in particular those with weak immune systems. There is currently no MRSA vaccine available.
Source: Bavarian Nordic
Drug Solutions Podcast: A Closer Look at mRNA in Oncology and Vaccines
April 30th 2024In this episode fo the Drug Solutions Podcast, etherna’s vice-president of Technology and Innovation, Stefaan De Koker, discusses the merits and challenges of using mRNA as the foundation for therapeutics in oncology as well as for vaccines.
A Novel, Enhanced, and Sustainable Approach to Audit Trail Review
July 4th 2025Eli Lilly and Company developed an innovative and sustainable approach to audit trail review (ATR) aimed at reducing the ATR burden while adhering to regulatory expectations and data integrity (DI) principles. The process has transformed employees' understanding of ATR and complemented the DI by design approach, leading to better system designs that meet expected controls and reduce non-value-added data reviews.
Drug Solutions Podcast: Gliding Through the Ins and Outs of the Pharma Supply Chain
November 14th 2023In this episode of the Drug Solutions podcast, Jill Murphy, former editor, speaks with Bourji Mourad, partnership director at ThermoSafe, about the supply chain in the pharmaceutical industry, specifically related to packaging, pharma air freight, and the pressure on suppliers with post-COVID-19 changes on delivery.
