Facilities for advanced therapies should be configurable to flexibly segregate production for late-stage and commercial multiproduct operation. Efficient design of a flexible and high-containment vaccine manufacturing facility that can meet all the challenges presented by the market requires a design philosophy that includes all the key control concepts: air, people, equipment, product, and liquid and solid waste. This article discusses best practices for such control and describes the use of modular, mobile cleanrooms.

Pharmaceutical Technology and BioPharm International

Vaccine Development and Manufacturing 2017

	When referring to this article, please cite it as T. Page, "Designing and Operating Flexible, High-Containment Vaccine Manufacturing," 

Pharmaceutical Technology and BioPharm International Vaccine Development and Manufacturing 2017 eBook

Contract Manufacturing, Biopharmaceutical Production

Contract Manufacturing, Sterile, Aseptic Processing

Facility Design and Engineering

Manufacturing

Manufacturing Services

Manufacturing, Biologic Drugs

Outsourcing

Pharmaceutical Technology-11-15-2017

A new facility type integrates next-generation mobile cleanroom systems.