|Articles|November 2, 2002
- Pharmaceutical Technology-11-02-2002
- Volume 26
- Issue 11
Estimation of Distribution Coefficients from the Partition Coefficient and pKa
Author(s)Douglas C. Scott, PhD
For a monovalent species, a simple calculation that does not assume partitioning of the ionized species in the oil phase can provide an accurate estimate of the distribution coefficient.
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