For a monovalent species, a simple calculation that does not assume partitioning of the ionized species in the oil phase can provide an accurate estimate of the distribution coefficient.
Douglas C. Scott, PhD
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Douglas C. Scott, PhD is a senior scientist at the Procter & Gamble company, Health Care Research Center, 8700 Mason-Montgomery Rd., Mason, Ohio 45040, tel. 513.622.2434, fax 513.622.2522.
Articles by Douglas C. Scott, PhD
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- Estimation of Distribution Coefficients from the Partition Coefficient and pKa
Published: November 2nd 2002 | Updated:
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