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The company installed a ZSE-3D twin screw extrusion system at its Somerville, NJ process laboratory.
On Aug. 27, 2018, Leistritz announced the installation of a ZSE-3D twin-screw extrusion system at its Somerville, NJ process laboratory. The system facilitates the development and production of 3D filaments from a co-rotating or counter-rotating twin screw extruder.
According to the company, direct extrusion of raw materials enables rapid product sampling and also results in one-less heat and shear history as compared to two-step processes, which is beneficial for heat and shear sensitive formulations.
The system features the following:
The company states that the system is suitable for in-line compounding of excipients with APIs, to quickly develop new filaments and formulations. Formulations can be modified extemporaneously for rapid sampling of filaments with different formulation percentages. A sample can be produced every 10 minutes. The filament system is configured for water-soluble and high-temperature applications.