March 2012 Editor's Picks: Products from EMD Millipore and Powder Systems

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Equipment and Processing Report

Equipment and Processing Report, Equipment and Processing Report-03-21-2012, Volume 0, Issue 0

PharmTech's monthly newsletter, Equipment and Processing Report, reviews the Editor's Picks for the March 2012 edition from EMD Millipore, ARTMiS, and Powder Systems.

EMD Millipore

Single-use powder mixing and delivery system now available in 1000-L size
EMD Millipore, the life-science division of Merck KGaA, added a larger, 1000-L system to its line of Mobius mixers, which already includes 100-, 200-, and 500-L sizes. The systems use integrated, single-use, powder delivery, mixing, and filtration technology, which gives biopharmaceutical manufacturers increased operational flexibility and decreases process and validation time and contamination risk.

“We are seeing an increased number of new applications for single-use technologies. It is now common to see single-use mixing systems and storage systems in pilot and production scale. With the introduction of the Mobius 1000-L single-use mixer, we are providing our customers with a wider range of volumes for increased flexibility to meet their specific processing needs,” say senior applications engineer Sue Walker and product development engineer John Saragosa of EMD Millipore.

Powder Systems

Automated milling system provides an advanced processing solution for jet milling of powders

Containment-unit supplier Powder Systems Ltd (PSL) collaborated with the suppliers of the ARTMiS Automated RealTime Milling System to provide a secure, isolated milling suite. The ARTMiS system, introduced last year, combines Sturtevant’s Micronizer Jet Mill, Malvern’s Insitec particle-size analyzer, and Schenck’s AccuRate PureFeed feeder in a fully automated system that simplifies and optimizes the jet-milling process. For high-potency or high-value materials that need containment of the jet-milling process, the PSL isolator provides containment to nanogram levels. The isolator was designed for enhanced operator viewing using an L-shaped window. The glove ports and cabinet-depth were designed ergonomically so that all parts of the isolator can be reached without stretching, says Stuart Evans, product engineer at PSL. An assured explosion protection system is integrated into the design. PSL offers an optional nitrogen purge system that is able to achieve less than 1% relative humidity.