A Novel Mathematical Method for Quantitative Expression of Deviation from Zero-Order Drug Release

News
Article
Pharmaceutical TechnologyPharmaceutical Technology-09-02-2001
Volume 25
Issue 9

Because drug delivery at a zero-order rate provides uniform concentration of a drug for absorption, this study attempts to identify a simple mathematical method to quantitatively express the deviation from zero-order kinetics.

External Link - article-2443.pdf

Articles in this issue
A Novel Mathematical Method for Quantitative Expression of Deviation from Zero-Order Drug Release
Six Sigma Can Give Contractors a Quality Advantage
Industry Changes OTC Labels as Deadline Approaches
A Report of the PQRI Workshop on Blend Uniformity
Are You Ready for Global Manufacturing?
Replacing the Animal Component in SerumEvaluating Raw Materials for Inclusion in Optimized Hybridoma Media
Pharmaceutical Coverage and Costs
Outsourcing Outlook
The Future State of Computer Validation, Part II: Increasing the Efficiency of Computer Validation Practices

Newsletter

Get the essential updates shaping the future of pharma manufacturing and compliance—subscribe today to Pharmaceutical Technology and never miss a breakthrough.

Subscribe Now!
Recent Videos
Lee Cronin, founder and CEO of Chemify
Related Content
A magnifying glass examining a vintage vaccine vial surrounded by four minimalistic chart icons, symbolizing healthcare, medicine, and analytics in the context of global health monitoring. | Image source: ©huiying - stock.adobe.com

ICH Q6B for Analytics

Richard Easton;Christopher Ziegenfuss
June 6th 2025
Article

ICH Q6B provides expectations and a clear framework for the structural characterization of biopharmaceutical products.

Drug Solutions Podcast: Applying Appropriate Analytics to Drug Development

Drug Solutions Podcast: Applying Appropriate Analytics to Drug Development

March 26th 2024
Podcast

In this episode of the Drug Solutions Podcast, Jan Bekker, Vice President of Business Development, Commercial and Technical Operations at BioCina, discusses the latest analytical tools and their applications in the drug development market.

Unidentified microbiologist is place the petri dish and tubes into incubator to incubate the culture of bacteria or fungi growth in appropriate condition, concept of microbial laboratory. | Image Credit: © Sukjai Photo – © Sukjai Photo – Stock.Adobe.com

Evolving Cleanroom Procedures and Sterility Challenges

Feliza Mirasol
May 6th 2025
Article

The shift toward personalized medicines poses new challenges in cleanroom protocols.

Macro view on vials | Image Credit: © yuriygolub - stock.adobe.com

Extractable and Leachable Challenges in Lyophilized Drug Products

Alan Xu;Piet Christiaens
April 5th 2025
Article

The authors examine the risks of extractables and leachables, and present solutions that emphasize the importance of a strategic, multi-prong approach.

Communication between the manufacturing plant and retail stores. | Image Credit: © Cagkan - © Cagkan - stock.adobe.com

Beckman Coulter Life Sciences Launches Modular Spectral Flow Cytometry Module, First of Its Kind in Industry

Feliza Mirasol
March 28th 2025
Article

The CytoFLEX mosaic Spectral Detection Module offers up to 88 channels for detection.

research, doctor, microscope, experiment, dx, digital transformation, data, analysis, science, researcher, graph, chart, pharmaceutical, pharmacy, medicine, information, development, research institute | Image Credit: ©metamorworks - stock.adobe.com

Full Tolerance Coverage Method for Assessing Uniformity of Dosage Units with Large Sample Sizes

Pramote Cholayudth
March 10th 2025
Article

The ‘full tolerance coverage method’ is introduced as a coverage estimation approach for assessing the uniformity of dosage units from large sample sizes, ensuring that no dosage unit exceeds the specification range.