Oral Low Molecular Weight Heparin Absorption From Solution and Solid Dosage Forms in Rat, Dog, and Monkey Models

March 1, 2002
Andrea Leone-Bay

Andrea Leone-Bay is a senior director of project management at Emisphere Technologies, Inc., 765 Old Saw Mill River Road, Tarrytown, NY 10591, tel. 914.785.4733, fax 914.593.8281.

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Linda Gerspach

Linda Gerspach is a research associate at Emisphere Technologies, Inc.

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Catherina O’Shaughnessy

Catherina O’Shaughnessy is a senior research associate at Emisphere Technologies, Inc.

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Rajesh Agarwal

Rajesh Agarwal is a director of pharma- ceutics R&D at Emisphere Technologies, Inc.

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Connie Rosado-Gray

Connie Rosado-Gray is a project coordinator at Emisphere Technologies, Inc.

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Theresa Rivera-Schaub

Theresa Rivera- Schaub is a project manager at Emisphere Technologies, Inc.

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Robert A. Baughman

Robert A. Baughman is a senior vice-president of development at Emisphere Technologies, Inc.

Pharmaceutical Technology, Pharmaceutical Technology-03-02-2002, Volume 26, Issue 3

The delivery agent-mediated transport of low moleular weight heparin across Caco-2 cells is accomplished without opening the junctions or adversely affecting the structural integrity of the cell monolayer.