The Usefulness of 0.45 &#181m&#150Rated Filter Membranes

A. Mark Trotter

A. Mark Trotter is the president of Trotter Biotech Solutions.

Laura A. Thoma, PharmD

Laura A. Thoma, PharmD, is director of the Parenteral Medications Laboratory, at the University of Tennessee, Memphis, TN.

Patrick J. Rodrigues, PhD

Patrick J. Rodrigues, PhD, is a research associate in the Department of Pharmaceutical Sciences at the University of Tennessee, Memphis, TN.

Pharmaceutical Technology, Pharmaceutical Technology-04-02-2002, Volume 26, Issue 4

In this study, the authors examine the suitability of 0.45 &#181m&#150rated filters to be used as sterilizing and bioburden-reduction filters against significant populations of organisms such as B. diminuta in a wide range of differential pressures.