Whitepapers

We provide a list of readily available high-quality biopharma ingredients used for in vitro diagnostics, vaccines, cell cultures and preservatives that we keep on hand to service our biopharma customers. All these raw materials have a very short lead time to suit your rapidly-changing manufacturing needs.

Our in-house experts, along with Cecile Bellamy from Pfizer, deep dive into the factors that are influencing our industry today and look at what trends are likely to impact us in the future. We cover topics including regulatory compliance, manufacturer flexibility & supply chain risk and debate the supplier vs partner relationship and the importance of collaboration as we face a challenging future.

Read a compelling, detailed Case Study about how an innovation partnership with Waters Corporation enhanced Alcami’s capacity, efficiency, and compliance-readiness for their pharmaceutical manufacturing and analytical services to differentiate their offerings and drive business growth.

Biologics manufacturers have been successful boosting yields and increasing throughput in upstream mAbs production. Those increased volumes create a new challenge: scaling downstream process chromatography to be as productive. This Avantor white paper details how technologies such as a novel protein A chromatography resin and the use of additives can improve efficiencies in this complex process step. The white paper also explores the benefits of expanding single-use and continuous processing systems to further streamline downstream production and improve cost profiles.

A present investigation aimed to evaluate the impact of commonly used different binder-diluent ratios on the tablet's mechanical strength to propose a binder-diluent scale.

Pediatric formulations have become increasingly important as the healthcare field recognizes the huge impact that strict patient adherence can have on a treatment’s efficacy. But to overcome the challenges of adherence in children, drug developers need to consider innovative new dosage forms that can deliver flexible and convenient medications for young patients.

Process equipment used in the healthcare and pharmaceutical industries follow rigid specifications for accuracy, consistency and cleanliness.

Review testing requirements for lab balances in the pharmaceutical industry described in the relevant pharmacopoeias and the associated certificates offered by Sartorius.

Developing more effective chromatography resins for mAbs downstream processing is important ⏤ but it's not the only way to improve impurity clearance. In this study of the use of additives to enhance resin performance, two mAbs chromatography resins were examined. Both were used for a capture step, and additives were screened to reduce the nonspecific binding of impurities. The goal of the study was to optimize chromatography steps and thus increase the capacity and removal of impurities.

Newer, more complex targeted therapies are entering clinical development at rapid speeds, requiring facilities to increase manufacturing capacity levels in order to keep up with demands and under the strictest levels of containment.

In this application note, we show the reproducibility of gene expression measurements from Well to Well on 384-well TaqMan Array Cards, and Gene Expression assay panels.

Real-time qPCR: an established genomic technology in the discovery & development of therapeutic monoclonal antibodies.

Developing and manufacturing biologics requires compliant technologies and methods that provide excellent accuracy, consistency, and quality control (QC) with continuous automation potential to ensure the best possible product is delivered in the right time frame. PCR methods that enable quantification of target nucleic acid sequences—namely quantitative real-time PCR (qPCR) and digital PCR (dPCR)—have become core technologies for delivering high-quality results in a range of applications throughout biologics development and biomanufacturing. qPCR and dPCR methods are the gold standards for sensitive, specific detection and quantification of nucleic acid targets, which are useful for QC testing a wide variety of biologic characteristics.

We effectively demonstrate that TaqPath BactoPure Microbial Detection Master Mix is ideally suited for applications in biopharmaceutical manufacturing. TaqPath BactoPure Microbial Detection Master Mix enables consistent and sensitive detection of relevant targets in biopharmaceutical cell samples.

Emergent CDMO offers development services, drug substance, and drug product manufacturing for biological products, from preclinical through commercialization. Download our overview brochure to learn more about our end-to-end service offerings.

Demand for nanoparticles in the biopharmaceutical industry is on the rise. Download this article to learn more about the benefits and challenges of nanoparticle production.

Emergent's Winnipeg site is home to the Cytiva® SA25 Aseptic Filling Workcell, a gloveless, robotic filling isolator. Download our facts sheet to learn about the benefits of utilizing isolator technology.

Review testing requirements for lab balances in the pharmaceutical industry described in the relevant pharmacopoeias and the associated certificates offered by Sartorius.

Learn more about the Capsugel® Enprotect™ capsule and our breakthrough enteric manufacturing technology.

Liposome extruders are mainly used for the liposome formulation and achieving uniform size distributions. It is an ideal instrument to generate nanoscale liposome formulations, and to prepare exosomes and artificial cell membranes. By utilizing the tracked-etched filter membranes, the liposome extruders are capable