Principles of Steam-In-Place

October 1, 2004
Jean-Marc Cappia

Jean-Marc Cappia is vice-president of marketing for fluid management technology at Sartorius Stedim Biotech FMT, Aubagne, France.

Pharmaceutical Technology, Pharmaceutical Technology-10-01-2004, Volume 2004 Supplement, Issue 7

Steaming-in-place (SIP) is a widely adopted method for the in-line sterilization of processing equipment. The main advantage of SIP relies on manipulation reduction and aseptic connections that might compromise the integrity of the downstream equipment.