Subathra Ramamoorthy, Veranova, on how forced degradation and trace impurity profiling in potent APIs shape regulator-ready analytical methods.
News|Articles|November 30, 2015
PTSM: Pharmaceutical Technology Sourcing and Management
- PTSM: Pharmaceutical Technology Sourcing and Management-12-02-2015
- Volume 11
- Issue 12
Software Corrects Spectra Data
Author(s)Pharmaceutical Technology Editors
KnowItAll spectroscopy software from Bio-Rad Laboratories corrects differences in spectra data.
KnowItAll spectroscopy software from Bio-Rad Laboratories is designed for spectral analysis, identification, search, data management, and reporting. The software supports multiple instrument vendor file formats and techniques.
The Optimized Corrections technology performs a computationally complex set of corrections on query and reference spectra in a search to find a match between the query and each reference spectrum. Multiple corrections are applied automatically to compensate for differences between spectra caused by the variability of different instruments, accessories and human error.
The offering includes two software applications, KnowItAll QC Expert and KnowItAll Deformulation Expert. The company has also added 90,000 reference spectra to its data collection.
Source:
Articles in this issue
almost 11 years ago
Lab Reactor Designed for Scale-upalmost 11 years ago
Instrument Measures Endotoxins at Point of Usealmost 11 years ago
Instrument Manufacturers Collaborate on Interoperabilityalmost 11 years ago
HTS Reader Features Three Light Sourcesalmost 11 years ago
“A Hit for Every Target” and Changing the Model for Pharma Innovationalmost 11 years ago
Researchers Identify Advances for Heterocyclic Chemistryalmost 11 years ago
CMOs Lead Ongoing Drive for Single-Use Adoptionalmost 11 years ago
System Automates Traceabilityalmost 11 years ago
Lufthansa Cargo Offers CSafe ContainersRelated to this article
Subathra Ramamoorthy, Veranova, on when to escalate to structural elucidation and pair orthogonal techniques when characterizing an impurity.
Nitin Kumar Swarnakar, PhD, global application lab manager at BASF, talks about spray drying for drying amorphous solid dispersions and Raman spectroscopy’s role as a quantitative analytical tool.
Nitin Kumar Swarnakar, PhD, global application lab manager at BASF in Tarrytown, spoke with PharmTech at AAPS PharmSci 360 about formulation and characterization challenges for amorphous solid dispersions.
FDA draft guidance on individualized genome editing lets BLAs add patient-specific variants without new trials, shifting evidence to CMC assay data.
Vibha Jawa, PhD, chief scientific officer at EpiVax, explains why the need for animal studies varies by modality and what it takes for organ-on-chip and other human-relevant models to replace these studies in IND-enabling toxicology work.
In October, FDA reorganized rare disease development around a fit-for-purpose framework and a new pathway for individualized gene editing. Regulators in Europe and the UK set out long-term plans for clinical trials, AI, and moving away from animal testing.
Clinical, manufacturing, safety, and commercial teams all lean on shared data. They need to agree on who publishes each data product, who can use it, and what evidence goes with it.
Trending on Pharmaceutical Technology
1
FDA’s New Inspection Playbook Counts Remote Assessments and MRA Reports Toward Facility Evaluations
2
Late-Phase Impurities Need Reference Standards: AAPS PharmSci 360 2026
3
RRP Accelerated Approval: What VOCERYQ Means for Manufacturing Teams
4
Who Answers for Your Data? Building a Life Sciences Data Mesh
5