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Recent Advances in Semisolid Dosage Forms for Dermatological ApplicationSemisolid dosage forms are advantageous in terms of their easy application, rapid formulation, and ability to topically deliver a wide variety of drug molecules.
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Functionality Testing of a Multifunctional Directly Compressible Adjuvant Containing Lactose, Polyvinylpyrrolidone, and Croscarmellose SodiumThe authors review their study that aimed to develop a coprocessed, directly compressible, multipurpose adjuvant that could serve as a diluent and built-in disintegrant.
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The Usefulness of 0.45 µm–Rated Filter MembranesIn this study, the authors examine the suitability of 0.45 µm–rated filters to be used as sterilizing and bioburden-reduction filters against significant populations of organisms such as B. diminuta in a wide range of differential pressures.
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Effect of Extragranular Microcrystalline Cellulose on Compaction, Surface Roughness, and In Vitro Dissolution of a Self-Nanoemulsified Solid Dosage Form of UbiquinonePowdered self-emulsified dosage forms provide an attractive alternative to filled-capsule preparations, but the selection of a proper excipient is crucial.
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Effect of Extragranular Microcrystalline Cellulose on Compaction, Surface Roughness, and In Vitro Dissolution of a Self-Nanoemulsified Solid Dosage Form of UbiquinonePowdered self-emulsified dosage forms provide an attractive alternative to filled-capsule preparations, but the selection of a proper excipient is crucial.
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The Usefulness of 0.45 µm–Rated Filter MembranesIn this study, the authors examine the suitability of 0.45 µm–rated filters to be used as sterilizing and bioburden-reduction filters against significant populations of organisms such as B. diminuta in a wide range of differential pressures.
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Oral Delivery of Macromolecular DrugsMacromolecular drugs are typically injected, but oral dosage forms are being developed to improve the treatment of gastrointestinal conditions such as inflammatory bowel disease.
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Oral Delivery of Macromolecular DrugsMacromolecular drugs are typically injected, but oral dosage forms are being developed to improve the treatment of gastrointestinal conditions such as inflammatory bowel disease.
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Oral Delivery of Macromolecular DrugsMacromolecular drugs are typically injected, but oral dosage forms are being developed to improve the treatment of gastrointestinal conditions such as inflammatory bowel disease.
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Oral Delivery of Macromolecular DrugsMacromolecular drugs are typically injected, but oral dosage forms are being developed to improve the treatment of gastrointestinal conditions such as inflammatory bowel disease.
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Application of API-in-Capsule Best Practices to Accelerate Drug Product DevelopmentAPI-in-capsule approaches enable pharmaceutical companies to quickly assess new drug candidates with reduced API consumption and to increase speed to clinic.
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Designing Combination ProductsAPI can be mixed with silicone and other polymers to create drug-delivery combination products.
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Designing Combination ProductsAPI can be mixed with silicone and other polymers to create drug-delivery combination products.
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Monitoring Blend Uniformity with EffusivityBy moving uniformity monitoring back to the blender phase, blend variations that result from factors such as particle distribution and environmental temperature and humidity can be identified early.
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Monitoring Blend Uniformity with EffusivityBy moving uniformity monitoring back to the blender phase, blend variations that result from factors such as particle distribution and environmental temperature and humidity can be identified early.
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Monitoring Blend Uniformity with EffusivityBy moving uniformity monitoring back to the blender phase, blend variations that result from factors such as particle distribution and environmental temperature and humidity can be identified early.
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Monitoring Blend Uniformity with EffusivityBy moving uniformity monitoring back to the blender phase, blend variations that result from factors such as particle distribution and environmental temperature and humidity can be identified early.
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Alteration in Dissolution Characteristics of Gelatin-Containing Formulations: A Review of the Problem, Test Methods, and SolutionsEventual change in the dissolution characteristics of some dosage forms, which is ascribed to cross-linking of gelatin, continues to present challenges to drug manufacturers. The authors discuss the causes, mechanisms, and solutions to the problem.
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Monitoring Blend Uniformity with EffusivityBy moving uniformity monitoring back to the blender phase, blend variations that result from factors such as particle distribution and environmental temperature and humidity can be identified early.
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Using Ion Mobility Spectrometry for Cleaning Verification in Pharmaceutical ManufacturingThis article discusses the use of ion mobility spectrometry as an alternative to high-performance liquid chromatography to reduce the amount of time spent on the cleaning verification process.
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Using Ion Mobility Spectrometry for Cleaning Verification in Pharmaceutical ManufacturingThis article discusses the use of ion mobility spectrometry as an alternative to high-performance liquid chromatography to reduce the amount of time spent on the cleaning verification process.
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Using Ion Mobility Spectrometry for Cleaning Verification in Pharmaceutical ManufacturingThis article discusses the use of ion mobility spectrometry as an alternative to high-performance liquid chromatography to reduce the amount of time spent on the cleaning verification process.
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Evaluation of Physical Characteristics of Dexlansoprazole Orally Disintegrating TabletsThis article describes the approaches used during the development of a dexlansoprazole delayed-release orally disintegrating tablet (ODT) to evaluate tablet size and texture as they relate to disintegration rate and patient experience; in addition, the resistance to alcohol was also characterized.
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Evaluation of Physical Characteristics of Dexlansoprazole Orally Disintegrating TabletsThis article describes the approaches used during the development of a dexlansoprazole delayed-release orally disintegrating tablet (ODT) to evaluate tablet size and texture as they relate to disintegration rate and patient experience; in addition, the resistance to alcohol was also characterized.
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Evaluation of Physical Characteristics of Dexlansoprazole Orally Disintegrating TabletsThis article describes the approaches used during the development of a dexlansoprazole delayed-release orally disintegrating tablet (ODT) to evaluate tablet size and texture as they relate to disintegration rate and patient experience; in addition, the resistance to alcohol was also characterized.
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Evaluation of Physical Characteristics of Dexlansoprazole Orally Disintegrating TabletsThis article describes the approaches used during the development of a dexlansoprazole delayed-release orally disintegrating tablet (ODT) to evaluate tablet size and texture as they relate to disintegration rate and patient experience; in addition, the resistance to alcohol was also characterized.
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Using Lab Informatics and Instrumentation to Optimize Upstream BioprocessingAdvanced technologies, such as artificial intelligence and synthetic biology, can be used to their full potential in upstream bioprocessing, provided that data and knowledge management can be effectively managed.
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Obtaining User-Defined Particle Size Distribution Using Dry GranulationThe author examines the effect of compaction force, gap width, and sieve setup on granule size.
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Paving the Way for Modernized Drug-Product Manufacturing Through ExcipientsCommonly referred to as the future of advanced pharmaceutical manufacturing, continuous manufacturing has gained major traction in the past 10 years to enable significant improvements in efficiency, safety, cost, and speed to market.
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Paving the Way for Modernized Drug-Product Manufacturing Through ExcipientsCommonly referred to as the future of advanced pharmaceutical manufacturing, continuous manufacturing has gained major traction in the past 10 years to enable significant improvements in efficiency, safety, cost, and speed to market.
