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News|Articles|April 1, 2002

Pharmaceutical Technology

  • Pharmaceutical Technology-04-02-2002
  • Volume 26
  • Issue 4

Alteration in Dissolution Characteristics of Gelatin-Containing Formulations: A Review of the Problem, Test Methods, and Solutions

Eventual change in the dissolution characteristics of some dosage forms, which is ascribed to cross-linking of gelatin, continues to present challenges to drug manufacturers. The authors discuss the causes, mechanisms, and solutions to the problem.
External Link - article-14096.pdf

Articles in this issue

over 24 years ago

Effect of Extragranular Microcrystalline Cellulose on Compaction, Surface Roughness, and In Vitro Dissolution of a Self-Nanoemulsified Solid Dosage Form of Ubiquinone

over 24 years ago

The Usefulness of 0.45 &#181m&#150Rated Filter Membranes

over 24 years ago

Outsourcing Outlook

over 24 years ago

Monitoring Blend Uniformity with Effusivity

over 24 years ago

Using Ion Mobility Spectrometry for Cleaning Verification in Pharmaceutical Manufacturing

over 24 years ago

Bush Budget Combats Bioterrorism, Promotes Drug Safety

over 24 years ago

E-Procurement — Successfully Using and Managing Reverse Auctions

over 24 years ago

Liposomes: A Review

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Power of Two One-Sided Tests with Unequal Variances
Equivalence test using two one-sided tests are widely used for demonstrating the comparability of treatment effects in different research fields. The method described in the manuscript aims to use simulations in Microsoft Excel to compute power for 2 one-sided tests for two groups with unequal variances.
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