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K. Venugopal is a postgraduate student from the National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar 160 062, India, presently working at Ranbaxy Research Laboratories (Gurgaon, India).
April 01, 2002
Eventual change in the dissolution characteristics of some dosage forms, which is ascribed to cross-linking of gelatin, continues to present challenges to drug manufacturers. The authors discuss the causes, mechanisms, and solutions to the problem.