Precise Control with Improved Drug Delivery
In pharma delivery, size matters. So, too, do the intricacies of dosage format, active ingredient compatibility, and effective delivery to patients—whatever their needs or preferences may be. Yet standard dosage forms haven’t always provided companies the options, flexibility, or performance to bring all those puzzle pieces together during therapeutic development. We spoke with Nathan H. Dormer, PhD, Director of Drug Product Development at Adare Pharma Solutions, to learn how this new technology platform is expanding the frontiers of therapeutic delivery and improving patients’ experience in the process.
The Role of On-Demand Manufacturing and Derisking in Accelerating Early Clinical Trial Success
June 4th 2025Small pharmaceutical companies are constantly seeking innovative solutions to streamline early clinical trials. Adaptive clinical trials offer important benefits to sponsors and patients, both from a commercial and ethical standpoint. These trials offer flexibility and efficiency, especially in the early stages, where trial protocols can be adjusted based on interim data, such as introducing new doses or modifying participant sample size. However, adjusting manufacturing demand during an adaptive trial can be complicated, and strict regulatory requirements present significant challenges. On-demand manufacturing provides a robust solution, allowing for real-time supply and demand adjustments and improved trial flexibility. This paper explores how on-demand manufacturing meets the operational needs of adaptive trials and aligns with regulatory expectations.
Fast and Efficient Sialic Acid Clone Selection Using Lectin-Based High-Throughput Screening
June 2nd 2025Glycosylation is a common and critical post-translational modification that affects protein function and therapeutic efficacy, making its monitoring and accurate quantification essential for drug development.
