Chromatography Solution for Biologic Drugs

March 2, 2021
Pharmaceutical Technology, Pharmaceutical Technology-03-02-2021, Volume 45, Issue 3
Pages: 12

The 3M Polisher ST from 3M Health Care is a single-use anion exchange (AEX) chromatography solution intended to replace the reusable AEX polishing column for biologic drug manufacturing.

The 3M Polisher ST from 3M Health Care is a single-use anion exchange (AEX) chromatography solution intended to replace the reusable AEX polishing column for biologic drug manufacturing. The new synthetic, fully encapsulated, single-use membrane chromatography solution contains two AEX-functional media: a quaternary ammonium functional nonwoven for the reduction of turbidity, DNA, and endotoxin; and a guanidinium-functional membrane for host-cell protein and virus reduction in a salt-tolerant manner.

Continuous bioprocessing allows facilities to reduce their size and cycle times, the compact product increases biomass production in therapeutic recombinant protein processes in all operating conditions.

3M Health Care

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