Crossflow Filtration System for Process Development

February 1, 2016
Pharmaceutical Technology, Pharmaceutical Technology-02-02-2016, Volume 40, Issue 2

Sartorius Stedim Biotech’s (SSB) Sartoflow Smart is a benchtop crossflow system for optimized ultra- and diafiltration applications.

Sartorius Stedim Biotech’s (SSB) Sartoflow Smart is a benchtop crossflow system for optimized ultra- and diafiltration applications. The system can be used in downstream processes, such as purification of vaccines, monoclonal antibodies, and recombinant proteins. The system is suitable for flexible use in laboratory environments for process development, clinical trials, and cGMP environments.

The system is equipped with a low shear 4-piston membrane pump that provides a wide range of flow rates. Users can select membrane surface areas from 50 cm² to 0.14 m². An optional peristaltic diafiltration pump is available to load product or buffer as a discrete process step. The system can be customized: conductivity, pH, or temperature probe can be installed in the recirculation vessel. The system can also be upgraded in the case of changing process requirements.

Sartorius Stedim Biotech 
www.sartorius.us

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