Vibha Jawa, PhD, chief scientific officer at EpiVax, explains why the need for animal studies varies by modality and what it takes for organ-on-chip and other human-relevant models to replace these studies in IND-enabling toxicology work.
|Articles|October 2, 2016
- Pharmaceutical Technology-10-02-2016
- Volume 40
- Issue 10
Double Planetary Mixers for Heavy Duty Mixing
The Double Planetary Mixers from Ross, Charles & Son are offered in 4-, 5-, 10-, and 25-gallon models for pilot-scale production of highly-filled pastes, dough-like materials, shear-sensitive gels, granulations, and powder blends.
The Double Planetary Mixers from Ross, Charles & Son are offered in 4-, 5-, 10-, and 25-gallon models for pilot-scale production of highly-filled pastes, dough-like materials, shear-sensitive gels, granulations, and powder blends. These mixers are also used for vacuum drying of heat-sensitive applications at relatively low temperatures. The blades are ideal for heavy-duty mixing of viscous materials up to six million centipoise, and the helical curve and graduated down-thrust cross-section of the high viscosity blades prevent product from climbing up into the cover. The mixers vacuum capability allows users to remove air from the batch before starting the agitators or during the mixing cycle, which results in a smooth void-free finished product without the need for additional defoaming or deaeration post-mixing.
Articles in this issue
about 10 years ago
Ophthalmic Drug Packaging: Safety Risks and Patient Acceptability Issuesabout 10 years ago
Improving Feeder Performance in Continuous Pharmaceutical Operationsabout 10 years ago
Protecting Parenterals in Primary Packagingabout 10 years ago
Manufacturers Face Major Changes under PDUFA VIabout 10 years ago
Defining Risk Assessment of Aseptic Processesabout 10 years ago
Fill/Finish Outsourcingabout 10 years ago
Calling All Authorsabout 10 years ago
Excipients for Formulation Successabout 10 years ago
Tracking a Global ProblemRelated to this article
Sanjay Konagurthu, PhD, senior director of Science and Innovation at Thermo Fisher Scientific, explains what teams need to do to ensure the usefulness of AI and what strides have been made with AI in regulatory submissions.
Pauric Bannigan, Intrepid Labs, explains where AI speeds formulation decisions, why data is the bottleneck, and how active learning trains models with far less data.
The new initiative aims to apply traceable AI and science to expand care worldwide by translating discovery into tools that accelerate drug development.
Sanjay Konagurthu, PhD, senior director, Science and Innovation at Thermo Fisher Scientific, provides an update on the progress of AI and machine learning used in drug delivery.
Stephanie Johnson, Pfizer, explains how off-platform triggers, single-owner risk registers, and traceable prior knowledge keep protein formulation programs on track.
Stephanie Johnson, Pfizer, discusses how platform formulations moved 2 Pfizer protein programs to IND in 8 months by redistributing, not removing risk.
Shubhajit Paul, a senior research fellow in Boehringer Ingelheim’s Department of Material Analytical Sciences, spoke with PharmTech at AAPS PharmSci 360 to explain how tabletability prediction can be improved for roller-compacted formulations.
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