Mastering Nitrosamines analysis: From Method Development To Analysis

The pharmaceutical industry’s concern around nitrosamines has only grown in recent years, necessitating more advanced analytical techniques to accurately and precisely detect low levels of nitrosamines and ensure regulatory compliance and safety. This webinar will discuss liquid chromatography with tandem mass spectrometry (LC-MS/MS) as the ideal technique for nitrosamines analysis, covering case studies, sample prep bottlenecks, and tips for reaching detection limits.

Register Free: https://www.pharmtech.com/pt_w/mastering-nitrosamine-analysis

Event Overview:

Nitrosamines have been a concerning topic in pharmaceuticals because they are potential carcinogens. Advanced analytical techniques such as liquid chromatography with tandem mass spectrometry (LC-MS/MS) enable precise and accurate detection of nitrosamines at low levels to support pharmaceutical safety and compliance. In this webinar, case studies on aspects of nitrosamine analysis—such as challenges with sample preparation, separation, and reaching required detection limits—will be discussed.

Key Learning Objectives:

• Learn how to optimize LC and MS conditions to harness the best separation, detection, and sensitive quantitation of nitrosamines in active pharmaceutical ingredients (APIs).
• Learn how to identify unknown impurities with reliable full-scan MS/MS data acquisition with MRM > EPI using QTRAP technology.
• Learn about performing accurate and reproducible quantitative analysis on a compliant-ready platform.

Who Should Attend:

• Scientists working in pharmaceutical, analytical, and R&D labs interested in nitrosamine methodology
• QA/QC managers involved in risk assessment

Speaker:

Lakshmanan Deenadayalan
Application Support Scientist
SCIEX

Lakshmanan Deenadayalan is a passionate scientist with 11 years of experience in the field of mass spectrometry (MS). His career began in the BeBa field, where he quickly developed a deep interest in analytical techniques and instrumentation.

Six years ago, Lakshmanan joined SCIEX, an industry-leading provider of MS solutions. He joined the company in a customer-facing role, which allowed him to work closely with clients and better understand their needs. His dedication to helping others and his expertise in the field soon led him to move into a technical marketing position. In this capacity, he works with both nominal and high-resolution mass spectrometers, assisting in the development and promotion of cutting-edge analytical tools.

Throughout his career, he has contributed 5 scientific publications and 30 technical notes, showcasing his commitment to advancing knowledge and sharing insights with the wider scientific community. His day-to-day responsibilities at SCIEX involve method development, customer troubleshooting, and training customers on the company’s state-of-the-art equipment.

Register Free: https://www.pharmtech.com/pt_w/mastering-nitrosamine-analysis