Pre-Clinical Small-Scale Custom Spray Dryer

Serán, a contract development and manufacturing organization that provides a variety of solid oral dosage forms including tablets, capsules, granules, and powder-in-bottle, has expanded its early development capabilities with the SD-5, a new pre-clinical small-scale custom spray dryer. The SD-5 is the sixth custom spray dryer in operation at Serán, which aims to achieve high yields with batch sizes <50 mg of APIs. This capability enables rapid formulation screening of spray-dried dispersions with minimal API. The SD-5’s design minimizes equipment surface area on which unrecoverable product can build up and provides containment for potent pre-tox compounds. Lead formulations can then be scaled up on Serán’s SD-45 and SD-90 spray dryers to produce larger batches and process transfer into clinical manufacturing.

Serán