Validation Changes to the USP Assay Method for Ibuprofen Tablets

Velagaleti,Ranga;Ward,James;Anderson,Pam;Massad,Lynn;Burns,Philip;

Validation Changes to the USP Assay Method for Ibuprofen Tablets

March 1, 2002

Ranga Velagaleti, PhD, James Ward, Pam Anderson, Lynn Massad, Philip Burns

Pharmaceutical Technology, Pharmaceutical Technology-03-02-2002, Volume 26, Issue 3

This study investigated the effectiveness of the direct extraction of tablets and shaking time on the disintegration of tablets, solubilization, and recovery of ibuprofen from tablets of various formulations, strengths, and spiked placebo.