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This application note demonstrates that the Agilent 6475 triple quadrupole LC/MS system can confidently quantify nitrosamine impurities at the low concentration levels specified by regulatory requirements. This method can be used to quantify these impurities in different ARB drug products, with some changes in chromatographic conditions based on the elution pattern of the drug product.

Webinar Date/Time: Thu, Feb 23, 2023 11:00 AM EST

Thursday, ​​​​July 21st, 2022 at 11am EDT|8am PDT|4pm BST|5pm CEST Learn about the use of molecular spectroscopy techniques – transmission Raman spectroscopy (TRS) and laser direct infrared (LDIR) – for solid-state analysis in pharmaceutical formulation development.

Thursday, July 14th, 2022 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST Join us to learn approaches for the accurate determination of mutagenic azido, NDSRI, and nitrosamine impurities in drug substances and products using LC–MS/MS.

Tuesday, July 12th, 2022 at 11am EDT|8am PDT|4pm BST|5pm CEST Dr. Meike Römer from Grünenthal Pharma, Germany, presents the company’s approach for the evaluation and implementation of transmission Raman spectroscopy for pharmaceutical content uniformity testing.

Wednesday, May 25, 2022 at 11am EDT|8am PDT|5pm CEST|4pm BST In the last few years, the issuance of the ISO 10993-18:2020 medical device guidance and several high-profile publications and round robin studies have resulted in the FDA increasing scrutiny of E&L analyses for both drugs and devices. Join our panel of industry experts to discuss these changes and to learn the direction E&L studies may take in the future.

Tuesday, October 26, 2021 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST Are you planning to turn your analytical HPLC method into a purification method? Are you converting your analytical-scale purification method to semi-prep or production scale? Learn how to set appropriate purification goals for purity, yield and throughput and what type of equipment will best fit your application.

Tuesday, September 28, 2021 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST In the last few years, the issuance of the ISO 10993-18:2020 medical device guidance and several high-profile publications and round-robin studies have resulted in the FDA increasing scrutiny of E&L analyses for both drugs and devices. Join our panel of industry experts to discuss these changes and to learn the direction E&L may take into the future.

Learn about the use of molecular spectroscopy techniques – transmission Raman spectroscopy (TRS) and laser direct infrared (LDIR) – for solid-state analysis in pharmaceutical formulation development. Live: US & Europe: Tuesday Sept. 29, 2020 at 9am EDT | 2pm BST | 3pm CEST, US: Tuesday Sept. 29, 2020 at 4pm EDT | 3pm CDT | 1pm PDT, Asia Pacific: Wednesday, Sept. 30, 2020 at 10:30am IST | 1pm CST | 2pm JST | 3pm AEST On demand available after airing until Sept. 30, 2021

This webinar will describe raw material verification testing through transparent and non-transparent packaging using the new Agilent Vaya handheld Raman system. True through-barrier analysis removes the need for sampling, increasing testing throughput without increasing costs—from clear glass vials to multilayer paper sacks. Live: US & Europe Broadcast: Thursday, Oct.1, 2020 at 9am EDT| 2pm BST| 3pm CEST, US Broadcast: Thursday, Oct. 1, 2020 at 4pm EDT | 3pm CDT| 1pm PDT, Asia Pacific: Friday, Oct. 2, 2020 at 10:30am IST| 1pm CST| 2pm JST| 3pm AEST On demand available after airing until Oct. 2, 2021

• How to balance compliance needs with creating useful SOPs. • Tips and tricks for ensuring consistency. • Why and how you should test your SOPs

Quality control plays a major role in the development of safe, high-quality pharmaceutical products. This PharmTech eBook on Pharma Quality Control Testing helps laboratories ensure they are up to date on the latest tools and techniques for achieving precise and efficient results in QC testing.

• Accelerated compliance for less expense. • Raman spec streamlines non-destructive processes for production/release

• Raman spectroscopy of streamlining pharma QC and formulation development • Implementing transmission Raman for fast content uniformity testing • Through-container identity verification of polysorbates 20, 40, 60, and 80