Ali Nokhodchi, PharmD, PhD, is an associate professor of pharmaceutics and visiting professor at King's College, Department of Pharmacy, School of Health and Life Sciences, Franklin-Wilkins Building, 150 Stamford St., London, Englad SE1 8WA.
Pharmaceutical Technology Europe
Water interacts with pharmaceutical solids at virtually all stages of manufacture, from synthesis of raw materials to the storage of the final dosage form. The interactions of water with powders is, therefore, a major factor in the formulation, processing and product performance of solid pharmaceutical dosage forms.
Three methods for microencapsulating paracetamol using cellulose acetate phthalate as the coating agent revealed significant differences in terms of drug content, microcapsule size, and drug release rate.
