Pharmaceutical Technology-06-02-2006

The laboratory supplier landscape is undergoing a radical makeover.

I always suspected that our purchasing manager had agreed to this just to save money . . .

Thermal effusivity and power consumption may help predict granulation end point in high-shear granulators. In this study, power consumption was monitored and compared with percent relative standard deviation (RSD) on thermal effusivity measured at-line. Lactose monohydrate, microcrystalline cellulose, and magnesium oxide were granulated, and the effect of load size on granule growth in a fixed-volume granulator was evaluated using three load levels. Load size, liquid addition rate, and impeller speed were measured, and the correlation among RSD on effusivity, power consumption, mean granule specific surface area, and granule compressibility index were determined.

Predictable outcomes lead to greater manufacturing efficiency and speed time to value.

Pharmaceutical Science & Technology News

Does "personalized medicine" mean personalized treatment or personalized molecules, custom made for a patient's specific biology?

CMOs account for 20–30% of biopharm production. Big Pharma also is filling the biologics supply chain.

Interphex provided an opportunity to examine the latest pharmaceutical packaging concepts and packaging machines.

The biggest single recent trend in outsourcing solid-dosage processing has been the movement toward discovery and synthesis of more potent active pharmaceutical ingredients.

If there's one word I (and probably most people) have come to fear more than all others, it's "failure." We've been conditioned since grade school that failure is shameful and punishment worthy. Maybe even something we should tuck away in our knapsack, sneak past Mom and Dad, tear into little pieces, and hide under the carpet.

ORA leadership looks to staff redeployment and risk management to ensure product quality despite diminishing resources.