Pharmaceutical Technology-09-02-2002

Pharmaceutical Technology

Mixed-Flow Exhaust Technology: A New Approach for Energy Savings and Pollution Abatement

September 02, 2002

Articles

26

9

Roof exhaust systems that incorporate mixed-flow impeller technology promote energy savings and cost containment.

Innovations of Membrane Chromatography for Biomolecular Purification

September 02, 2002

Columns

26

9

The high dynamic binding capacity of membrane chromatography makes this system suitable for several biopurification applications.

New Syringe Designs Combine Prefilled Convenience with Safety

September 02, 2002

Columns

26

9

Prefilled-syringe manufacturers implement built-in safety features to prevent potential needlestick injuries.

A Prototype Intelligent Hybrid System for Hard Gelatin Capsule Formulation Development

September 02, 2002

Articles

26

9

Decision-making tools such as expert systems and artificial neural networks can be integrated to facilitate the development of optimal formulations of hard gelatin capsules.

An Overview of the Validation Approach for Moist Heat Sterilization, Part I

September 02, 2002

Articles

26

9

Part I of this article discusses examples for cycle types used in moist heat sterilization, parameter requirements for a standard cycle as defined by pharmacopeias, methods used to design sterilization cycles, and various approaches used to measure the efficiency of the sterilization process.

Outsourcing Outlook

September 02, 2002

Contract Services

26

9

The author discusses the potential effect on CROs of pending major-pharma mergers and consolidations.

Spreading of Semisolid Formulations: An Update

September 02, 2002

Articles

26

9

Spreadability of a semisolid forrmulation is affected by factors such as formulation characteristics, rate and time of shear, temperature, site of application, and the presence of various additives.

Auditing Your Contractor

September 02, 2002

Contract Services

26

9

When choosing a CRO, take the time to conduct an in-depth evaluation of each department, paying special attention to the quality and training of its personnel.

Attack Mounts on Drug Prices

September 02, 2002

Columns

26

9

Congress debates legislation for a Medicare drug benefit while the industry expresses concerns about import control, drug counterfeiting, and patent rights.