Pharmaceutical Technology-12-02-2004

Pharmaceutical Technology

Acceptable Analytical Practices for Dissolution Testing of Poorly Soluble Compounds

December 02, 2004

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This article provides guidance for developing dissolution testing for poorly soluble compounds. It is the second of a series of articles based on material from a 2003 PhRMA workshop about acceptable analytical practices.

The Preparation and Evaluation of Albendazole Microspheres for Colonic Delivery

December 02, 2004

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Microspheres of Eudragit RL were developed for colonic delivery of albendazole. The effects of polymer concentration, stirring rate, and concentration of emulsifier on particle size and drug loading were studied. A comparative in vitro drug release study of the optimized formulation was carried out.

In the Spotlight-December 2004

December 02, 2004

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Pharmaceutical Science & Technology Innovations

In Between the Light and the Dark: Developments in Photosensitive Pharmaceuticals

December 02, 2004

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Researchers are improving photodynamic therapies with new photosensitizers and light sources for deeper tissue penetration, more site-specific treatments, and reduced side effects.

Safety Problems Roil Pharma and FDA

December 02, 2004

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Blockbuster drugs turn out to be risky business, while contamination problems shut down flu vaccine production.

December 2004

December 02, 2004

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Pharmaceutical Science & Technology News

Robust CRO Market Is Driving New Merger and Acquisition Activity

December 02, 2004

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The blockage in the new product pipeline may be breaking. CROs report increased demand for late-stage development services in their latest round of earnings reports.

The Seventh Annual International Employment Survey

December 02, 2004

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More than 1500 pharmaceutical industry employees worldwide provide a personal view into the issues that matter most in the workforce, including salary and benefits, skills and education, and perspectives on the current job market.

Pharmaco-Fakery

December 02, 2004

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On the other hand, if we don't keep up the pressure on counterfeiting in the US, we may share the plight of the developing world, where nearly 25% of all drugs sold are fakes.