Bosch Displays Pharma Manufacturing Solutions at CPhI 2018

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At CPhI World-Wide 2018, Bosch will display its Xelum R&D for laboratory-scale continuous OSD production and its new data-mining service for equipment and process troubleshooting.

At CPhI 2018 in Hall 4, booth G22, Bosch Packaging Technology’s new Xelum R&D, a laboratory system for continuous manufacturing of oral solid-dosage (OSD) forms, will be on display for the first time. Visitors can also see how the Bosch Pharma Service and Industry 4.0 solutions support pharmaceutical manufacturers in increasing transparency and efficiency of their laboratory processes. 

“The Xelum R&D is the first R&D machine to combine charging, dosing of several ingredients, and blending, with granulation, drying, and discharging in one unit,” Fritz-Martin Scholz, product manager at the Bosch subsidiary Hüttlin, explained in a press release. “In contrast to continual mass flow, the Xelum R&D doses excipients and active ingredients as a discrete mass. This way, customers can dose even smallest amounts of APIs of less than one percent. Individual packages, so-called X-keys, continuously run through the process chain and are removed successively from the machine as packages into bins.” 

The X-key approach makes the product traceable at all times. It reduces the system’s failure susceptibility and process complexity, while increasing the product’s accuracy and quality. Time-consuming scale-up is not needed, because the laboratory device uses the same components as the Xelum production platform. The identical process parameters can be directly transferred, which leads to a reduced development time. 


Source: Bosch