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|Articles|August 1, 2011
Pharmaceutical Technology Europe
- Pharmaceutical Technology Europe-08-01-2011
- Volume 23
- Issue 8
Controlled Crystallization During Freeze-Drying
The authors discuss the preparation of lipophilic drug nanocrystals by controlled crystallization during freeze-drying.
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By Hans de Waard, Niels Grasmeijer, Wouter L.J. Hinrichs, Thomas De Beer and Henderik W. Frijlink
The authors discuss the preparation of lipophilic drug nanocrystals by controlled crystallisation during freeze-drying (CCDF). In-line Raman spectroscopy was used to monitor the crystallisation of the drug during freeze-drying to elucidate how the size of the drug crystals could be controlled. A three-way nozzle was used to create a spray freeze-drying process suitable for large-scale production.
This article was also published in our US sister publication Pharmaceutical Technology and can be read
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Improving API Synthesisabout 15 years ago
Understanding Fluidized-Bed Granulationabout 15 years ago
Controlled Release from Porous Platformsabout 15 years ago
Movin' On Outabout 15 years ago
The Many Varieties Of 'Emerging'about 15 years ago
Newsabout 15 years ago
Managing Information Overloadabout 15 years ago
The Importance Of Filter Testingabout 15 years ago
Making A Mark In Emerging Marketsabout 15 years ago
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