Hovione's $35M CDC Flex line links spray drying to tablets, designed to eliminate scale-up under FDA Q13 guidance.
|Articles|August 1, 2011
Pharmaceutical Technology Europe
- Pharmaceutical Technology Europe-08-01-2011
- Volume 23
- Issue 8
Understanding Fluidized-Bed Granulation
This study demonstrates the beneficial use of a spatial-filter velocimetry particle-size analyzer during granulation.
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By A. Burggraeve, T. Van Den Kerkhof, M. Hellings, J.P. Remon, C. Vervaet and T. De Beer
The authors incorporated a particle-size analyser into a laboratory-scale top-spray fluid-bed granulator to monitor granule size distribution (GSD) continuously during granulation. A two-level full-factorial design was used to study the influence of several process and formulation variables on the end-product GSD, measured in-line with spatial-filter velocimetry (SFV).
This article was also published in our US sister publication Pharmaceutical Technology and can be read
Articles in this issue
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Improving API Synthesisabout 15 years ago
Controlled Release from Porous Platformsabout 15 years ago
Controlled Crystallization During Freeze-Dryingabout 15 years ago
Movin' On Outabout 15 years ago
The Many Varieties Of 'Emerging'about 15 years ago
Newsabout 15 years ago
Managing Information Overloadabout 15 years ago
The Importance Of Filter Testingabout 15 years ago
Making A Mark In Emerging Marketsabout 15 years ago
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