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Shimadzu's Nexera-i MT is based on the very successful i-Series platform of compact HPLC and UHPLC systems launched in 2014. The instrument offers enhanced functionality to support the transfer of existing HPLC to faster UHPLC methods while assuring high cross-compatibility between the old and new method conditions. Nexera-i MT targets a wide range of industries including pharmaceuticals, chemicals and foods.
Nexera-i MT features two independent and dedicated flow lines, one for UHPLC and the other for HPLC analyses. Newly developed Analytical Conditions Transfer and Optimization (ACTO) technology minimizes the effect of system volume differences on analytical results. In addition to drastic improvement of efficiency and quality of method development and transfer efforts in quality control departments, Nexera-i MT's dual flow lines also maximize operational efficiency. They enable a single instrument to run both HPLC and UHPLC analyses, as opposed to separate dedicated instruments for each analysis.
In recent years there has been a strong focus on the use of UHPLC instruments and small particle columns to develop faster and better analytical methods that improve efficiency and throughput, especially in R&D environments. However, many of the analytical methods used in quality control laboratories, including those listed in the pharmacopeia, are conventional HPLC methods. Transferring these HPLC methods to UHPLC and validating the new methods is a time consuming and labor intensive task.
The Nexera-i MT incorporates two analytical flow lines with different system volumes into a single compact integrated LC. By switching automatically between the flow lines, Nexera-i MT seamlessly performs both HPLC and UHPLC analyses, preserving the relative separation pattern by compensating automatically for differences in system volume. Consequently, Nexera-i MT achieves exceptional analytical reproducibility when switching from a system with large volume to a system with small volume or vice-versa. The same technology also allows Nexera-i MT to match any existing HPLC or UHPLC method, eliminating the need to consider and to carefully match plumbing to achieve identical system volumes between instruments.
Nexera-i MT provides technologies, features and functionalities which support efficiency, method conversion, productivity and reduced solvent consumption:
Advanced design for the "computer-less, hassle-free laboratory"
The central concept driving the development of all i-Series instruments is "to free operators from the laboratory". The core features of the i-Series instruments, such as high reliability, small footprint and intuitive operation via touch-panel and smart device functionality, are highly praised by users of these instruments. The i-Series has been accepted globally in a wide range of industries including pharmaceuticals, chemicals and foods. In 2015, the i-series has been awarded with the Good Design Award donated by the Japan Institute for Design Promotion. The i-Series is not just an analytical instrument; its advanced design heralds the future analytical environment, the "computer-less, hassle-free laboratory."
For more information please visit www.shimadzu.eu