Rapid Screening for Elemental Impurities using ICP-MS

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Pharmaceutical TechnologyPharmaceutical Technology-11-15-2014
Volume 2014 eBook
Issue 3

The authors describe a rapid, single-point calibration approach for ICP–MS analysis of raw materials used in drug product manufacturing.

 

The official implementation of United States Pharmacopeia (USP) <232> will require measurement of elemental impurities using inductively coupled plasma–mass spectrometry (ICP–MS). The authors describe a rapid, single-point calibration approach for ICP–MS analysis of raw materials used in drug product manufacturing.

 

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