Allen C. Templeton, PhD

The miniaturization of preclinical safety assessment studies using a microfluidic chip system and optical microscopy can help reduce compound requirements, time, and costs in formulation development.

Frequency modulation spectroscopy is a nondestructive technology for determining the water activity of pharmaceutical samples. This article discusses the various pharmaceutical applications of frequency modulation spectroscopy, offers comparisons with various traditional water activity measurement techniques, and presents an assessment of various instrument performance elements.

The rapid and accurate determination of headspace oxygen in various pharmaceutical packaging forms poses unique analytical challenges.