Advanced dynamic process control of a fluid-bed granulation process using PAT data improves product quality.
Ian Jones
Advertisement
Ian Jones, PhD, is founder and CEO of Innopharma Technology and Innopharma College of Applied Sciences, Dublin
Articles by Ian Jones
A process control system based on PAT can compensate for variations in particle size, resulting in more consistent coating thickness in a Wurster coating process.
Process analytical technology, based on monitoring particle size distribution and tracking coating thickness measurements in real time, can be used to predict the dissolution of polymer-coated multiparticulates.
Advertisement
Latest Updated Articles
Predicting Multiparticulate Dissolution in Real Time for Modified- and Extended- Release FormulationsPublished: April 1st 2017 | Updated:
Exploring a Modern Control Strategy for Wurster CoatingPublished: August 2nd 2018 | Updated:
Self-Guided Control of a Fluid Bed Granulation ProcessPublished: January 2nd 2020 | Updated:
Advertisement
Advertisement
Trending on Pharmaceutical Technology
1
Implications on SMA Care of High-Dose Nusinersen
2
Shifting from Trial-and-Error to Rational Design Drives Efficiency in Pharmaceutical Formulation
3
How Therapeutic and Analytical Advancements Help Drug Substance Testing Evolve
4
Overcoming Drug Interference in an IND-Track ADA Assay
5
