Johannes G. Khinast

Optical coherence tomography can improve quality control and development of coated dosage forms by allowing film thickness to be measured in real time.

This novel technology was developed in response to challenges involved in conventional manufacturing of multilayer tablets, including in-line control of the tablet weight, the tendency to delamination, direct contact between the two tablet layers, and cross contamination.

A techno-economic profiling method supports pharmaceutical process development by helping identify the best manufacturing approach.