Steriline S.r.l.

The primary packaging of personalized high-value therapies at CPHI Barcelona 2023.

Robotics and isolators are an increasingly popular combination in the pharmaceutical industry due to the rising number of high-value therapies, such as Cell and Gene Therapies (CGTs), which are proving to be valid allies both against cancer and for patients with rare and ultra-rare diseases.

The adoption of isolators guarantees a Grade A environment during the sensitive manipulation of the products, limiting the risk of contamination and reducing the area where an aseptic environment must be established as required by cGMPs. Robots, conceived to operate in a sterile environment and to handle various types of containers, provide autonomy and automatic adaptability to the different solutions required to fill the exact quantities, according to the customers’ defined recipes.

With the aim to minimise rejects of any kind of high worthy products, Steriline relies also on a zero-loss philosophy, which provides to machines the intelligence to detect filling and capping inaccuracies during the primary packaging and to re-process each single container.

At CPHI Barcelona, Steriline will display the RVFCM2 that integrates robotics and isolators with its zero loss philosophy. Meet Steriline at stand 3T41, Pharma Machinery and Equipment area.

Steriline :: Pharmaceutical Aseptic Processing Equipment

Articles

Robotics and isolators are an increasingly popular combination in the pharmaceutical industry due to the rising number of high-value therapies, such as Cell and Gene Therapies. 

Robotic Vial Filling and Capping Machine (RVFCM2) under isolator 

Fig. 1 - Robotic Vial Filling Machine (RVFM5), view from the tunnel

At Interpack 2023, Steriline (Hall 16, Booth 16B15) will welcome visitors and showcase a Robotic Vial Filling Machine and two additional innovative systems developed internally by the company’s R&D team to cover the current market needs and optimise the packaging processes.

The RVFM5 was designed to fill vials in bulk. It is equipped with five filling and stoppering heads, and vials are moved with a robotic arm, which provides advantages such as improved flexibility in glassware management, higher safety in product handling (which protects both drug and personnel), enhanced quality of the process not affected by human errors and contamination.

In addition to the above, a robotic assembly system for volumetric pumps will show at the booth how machine downtime can be reduced without sterility breaks when replacing volumetric pumps between two production cycles that require different doses. Last but not least, an exclusive unveiling of a new servo platform filling machine designed specifically for the small batch filling of high-value product, ideal for the Cell & Gene Therapy market, will be on display in a dedicated “innovation area”.

At Interpack 2023, Steriline (Hall 16, Booth 16B15) will welcome visitors and showcase a Robotic Vial Filling Machine and two innovative systems developed internally by the company’s R&D team.

Steriline’s R&D Innovation at Interpack 2023

	STERILINE is proud to introduce its new Robotic Vial Filling and Capping Machine for injectable products fully under in-house engineered and manufactured Isolators integrated with the latest VHP technology.

	The machine was designed and manufactured jointly with the German pharmaceutical company AqVida.

		3 VHP resistant robotic arms from STÄUBLI Robotics based in Switzerland

		Peristaltic pumps actuated by servomotors, that allow precise filling and easy adjustment of the pumps by means of the HMI

		“No loss / zero waste philosophy” resulting in all missing stoppers / caps being collected and re-applied during the process

		100% in-line Check Weighing System integrated in the filling station

		The vials range that can be treated goes from 2ml to 100ml, without changing any format parts, with an estimated output of approx. 6.000 vials/h satisfying at the best the customer requirements in terms of flexibility on the one hand and efficiency on the other

	The line is installed in the new AqVida plant in Dassow.

	Company name: Steriline Srl
	Website: www.steriline.it
	E-mail: 

ref="mailto:mirko.monti@steriline.it">mirko.monti@steriline.it

Steriline is an expanding European manufacturer founded in the Lake Como area in 1989, highly specialized in the production of complete lines for the aseptic processing of injectable products, supplying pharmaceutical companies worldwide.