Pharmaceutical Technology-03-02-2007

Pharmaceutical Technology

Shifting Patterns in Sourcing

March 02, 2007

Articles

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The pharmaceutical supply chain lengthens as generic drug manufacturers build production platforms offshore and CMOs position in India and China to meet demand for lower-cost production.

Packaging Trends

March 02, 2007

Packaging Forum

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3

Security, the environment, aging populations, the bio-boom, and cost control are just a few of the drivers that will influence pharmaceutical packaging for the remainder of this decade.

Process Patent Protection: Characterizing Synthetic Pathways by Stable-Isotopic Measurements

March 02, 2007

Articles

31

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The authors describe the methods by which precise analyses of stable-isotopic abundances can be used in security and forensic applications for pharmaceutical materials. These methods include product and process authentication of raw materials, pharmaceutical intermediates, drug substances, formulated drug products, and synthetic pathways. Collectively, these methods can be used to investigate and mitigate patent infringement. In the future, more complete examples will be presented containing full isotopic results and the application of the methods described in this article.

Pursuits of Business

March 02, 2007

This Time Around

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3

The Parenteral Drug Association recently held its first global conference on emerging manufacturing technologies. Among the presentations were those discussing the latest in disposable technologies, aseptic filling and closing, and barrier systems. Clearly, technology vendors have stepped up efforts to streamline processes and better handle complex drug products.

The Advantages of Restricted-Access Barrier Systems

March 02, 2007

Articles

31

3

Filling machines often are installed in sterile rooms and separated by isolators to prevent contamination. These methods have certain drawbacks, including making interventions more difficult. Restricted-access barrier systems are an alternative that ensures sterility and facilitates interventions.