The evaluation of the intrinsic dissolution rate of an active pharmaceutical ingredient can be used to demonstrate chemical purity and equivalency. The authors used a rotating disk system and a stationary disk system to determine the intrinsic dissolution rates of various model drugs.
Using formulations containing various types of lactose and dibasic calcium phosphate, the authors investigated the effects of lubricant level, lubrication time, and compression speed on tablet weight, hardness, and friability.
Special considerations and cautions must be adhered to when designing virus safety studies and developing appropriate virus contamination control programs.
The author reviews year-to-date progress and growth in the pharmaceutical outsourcing industry.
FDA's new initiatives for the safe use of prescription drugs try to balance manufacturers' concerns about increased regulations with a low-risk approach to patient safety.
Cyclic olefin copolymer (COC) resins are showing a number of benefits that could propel their usage in syringe bodies, blister packs, and other packaging components.
Numerous risks are inherent to the process of outsourcing. The first line of defense for all parties is continuous diligence.
Transmucosal routes of drug delivery offer distinct advantages over peroral administration for systemic effect. The authors review buccal drug delivery and discuss the current status of buccal permeation enhancers.
