Development

Articles

The decision to move forward in Phase III development stems from the threat of resistance to current malaria treatment growth. 

Phase III Study for Novel Ganaplacide/Lumefantrine-SDF Combination in Adults, Children with Malaria Announced

Markus Hörburger is product and service manager Secondary Packaging & Device Assembly at Vetter.

The author describes how to seize market opportunities while navigating the requirements of both drug therapies and delivery devices.

Converting Injectable Therapies to Combination Drug-Device Products

The two companies signed an exclusive collaboration agreement for the Aidaptus auto-injector.

Owen Mumford and Stevanato Group Collaborate on Auto-Injector

AstraZeneca reports that its combination antibody therapy, AZD7442, reduced chances of severe COVID-19 or death by as much as 67%.

AstraZeneca’s AZD7442 Clinical Trial Meets Primary Endpoint

Editor of Pharmaceutical Technology Europe

Bi-layer tablets are an under-utilized option that can be employed to help reduce treatment burden, but their formulation is more complex than for conventional monolayer products.

Formulating Tablets Layer by Layer

The European Medicines Agency’s Committee for Medicinal Products for Human Use has recommended the approval of AstraZeneca’s Qtrilmet (metformin hydrochloride, saxagliptin, and dapagliflozin) modified-release tablets for treating type-2 diabetes.

AstraZeneca’s Combination Diabetes Pill Recommended for Approval in EU

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

A design strategy can ensure conflicting properties are managed appropriately for multi-API controlled-release formulations.

Combo Drugs Require a Complex Design Approach

Empty and prefilled syringes must pass a range of quality control tests.

Test Methods and Quality Control for Prefilled Syringes

Jennifer Markarian is manufacturing editor of Pharmaceutical Technology.

Using training devices may ease patient anxiety about using autoinjectors and prefilled syringes, potentially leading to improved patient adherence.

Autoinjector Training May Lead to Patient Adherence

Susan Haigney is managing editor of Pharmaceutical Technologyand Pharmaceutical Technology Europe, susan.haigney@ubm.com.

FDA Commissioner Scott Gottlieb has been promoting drug market competition in recent months that includes new guidance documents and targeted advisories to support R&D of complex drugs and combination products. 

Formulation and Drug Delivery, Combination Drugs