2026 approvals, clinical data, and licensing deals are advancing subcutaneous biologics, reducing patient burden, and reshaping biopharma drug strategy.
News|Articles|December 1, 2024
- Pharmaceutical Technology, December 2024
- Volume 48
- Issue 12
- Pages: 8
Coated Plungers for Large Volume Biologics
Author(s)Pharmaceutical Technology Editors
Datwyler has launched new coated plungers in its NeoFlex line that are suitable for large volume biologics.
Datwyler’s newly launched coated plungers in the NeoFlex line come in sizes fit for containers aimed at large-volume auto-injectors and wearable devices. The new prefilled syringe 10 mL with its NeoFlex Cartridge Wearable 10 mL is designed for high quality and safety standards with the new plungers, which ensure the stability and safety of large-molecule drugs. These plungers are completely covered in a non-fluorosurfactant grade fluoropolymer coating, which prevents rubber particles from shedding and minimizes degradation from extractables and leachables. The plungers are inherently lubricious, which eliminates the need for silicone to ensure smooth operation inside the syringe or cartridge barrels. This characteristic also supports compatibility with complex formulations, which is especially crucial for the effective delivery of a highly sensitive, highly viscous biologic.
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European Biotechs Unlocking Parkinson’s Diseasealmost 2 years ago
Integrating Advanced Technologies for Pharma Analysisalmost 2 years ago
Exploring Opportunities for LNP Delivery in mRNAalmost 2 years ago
Leveraging Advancements in Bioanalytical Testingalmost 2 years ago
Advancing the Precision Oncology Agenda in Europealmost 2 years ago
Rethinking Drug Pricingalmost 2 years ago
New Year, New PTERelated to this article
This week, the FDA opened applications for its Expedited IND Pilot, quality experts presented at the PDA/FDA Joint Regulatory Conference, and Hovione expanded its spray drying capacity.
The recently opened NJ spray drying facility doubles capacity for amorphous solid dispersions, addressing solubility limits in roughly 70% of small-molecule pipelines.
Sanofi will transfer 20 mature medicines and three manufacturing sites to Cheplapharm for a 26.4% equity stake, closing by Q3 2027.
On PharmTech.com this week, coverage of upcoming events continued, experts continued to discuss the use of AI in pharma, and validation in oral solid dosage product production was emphasized.
Christy Owings, Thermo Fisher, on why early supply chain partnership and site visits prevent costly eCOA and clinical trial delays.
Christy Owings, Thermo Fisher, on how AI complements clinical supply chain expertise, streamlines site logistics, and tracks shifting biotech markets.
Christy Owings, Thermo Fisher, speaks on why importer of record strategy and vetted local partners are key to reliable clinical trial supply chains.