Development

Articles

In this collaboration, Takeda will utilize Poseida's biodegradable DNA and RNA nanoparticle delivery technology and other proprietary genetic engineering platforms for the research and development of gene therapies.

Poseida Therapeutics and Takeda Partner to Develop Non-Viral In-Vivo Gene Therapy Programs

Glenmark Pharmaceuticals has partnered with SaNOtize to manufacture, market, and distribute NONS to India, Singapore, Malaysia, Hong Kong, and more.

Nitric Oxide Nasal Spray for COVID-19 to Be Distributed to India and Other Asia Markets

GSK announced that FDA has approved a new indication for Nucala (mepolizumab), a monoclonal antibody that targets interleukin-5.

FDA Approves GSK’s Treatment for Chronic Rhinosinusitis with Nasal Polyps 

In combination with etoposide and either carboplatin or cisplatin, Imfinzi has been approved in the first-line setting of ES-SCLC by China’s National Medical Products Administration.

AstraZeneca’s Extensive-Stage Small Cell Lung Cancer Treatment Approved in China

The investment will expand and upgrade manufacturing capacity and technology for pre-fillable syringes and will also includes a new manufacturing facility in Europe. 

BD to Invest $1.2 Billion Over Four Years in Pre-Fillable Syringe Manufacturing Capacity 

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

Excipients must be carefully chosen to ensure optimum protection for vaccines and live biotherapeutic products.

Factoring Stability in the Biologic Drug Mix

The new line has the ability to aseptically fill powder, liquid, suspension, and combination forms into vials in clinical or commercial batch sizes. 

Evonik Qualifies Filling Line for Parenteral Drug Products at its Alabama Facility 

The new facility in Grand Rapids, MI, is part of the CDMO’s aggressive expansion plan.

Grand River Aseptic Manufacturing Opens Large-Scale Injectable Fill/Finish Facility

The authors compare formulations containing citrate with other buffers in reducing subcutaneous injection-site pain and discuss a formulation and excipients selection strategy.

Approaches to Alleviating Subcutaneous Injection-Site Pain for Citrate Formulations

The right approach to biological safety cabinets, and collaboration between engineers and those who will operate the equipment, is crucial to preventing cell-culture contamination. 

Formulation and Drug Delivery, Parenterals