|Articles|December 11, 2015

Aptar Pharma presents a step change in the performance of DF30Plus for pMDIs incorporating COC

Author(s)Aptar

This new DF30Plus metering valve version incorporates a Cyclic-Olefin-Copolymer (COC) neck gasket to further enhance its performance. It is the result of continuous improvement to today's world leading DF30 technology platform.

 

 

Louveciennes, December 7, 2015 – Aptar Pharma, a global solution provider of innovative and proven aerosol, injection and spray delivery systems for biotech, healthcare and pharma products, presented its latest innovation, DF30Plus with COCe, at the Drug Delivery to the Lungs (DDL) scientific conference in Edinburgh, Scotland from December 9 to December 11, 2015.

 

This new DF30Plus metering valve version incorporates a Cyclic-Olefin-Copolymer (COC) neck gasket to further enhance its performance. It is the result of continuous improvement to today's world leading DF30 technology platform.

 

Aptar Pharma, a worldwide leader in innovative and proven inhalation drug delivery devices for Asthma and Chronic Obstructive Pulmonary Disease (COPD)

 

Aptar Pharma is the worldwide leader in aerosol metering valves for pMDIs for the treatment of Asthma and COPD. Aptar Pharma’s metering valves are considered the “go to” solution for major branded pharmaceutical companies and generic producers across the globe.

Each year, several hundred million metering valves are produced in Aptar Pharma’s three manufacturing facilities strategically located across Europe and Asia.  Aptar Pharma is the only metering valve supplier that designs, develops and manufactures its own elastomer gaskets – a key component of the valve - within its unique in-house Elastomer Center.

 

DF30Plus with COCe: ultra-clean, robust and versatile

 

Aptar Pharma’s DF30 metering valve technology platform has been the industry gold standard for more than 20 years and we are constantly striving to optimize our DF30 product offering.

COC is a well-known and characterized material used for injectable drug containers. COCe is a specific version of COC that has unique elastomeric properties while being ultraclean and inert.

 

The new version of DF30Plus that incorporates a neck gasket manufactured with COCe offers several key benefits:

 

- Step change improvement as a barrier to leakage

- Ultra low extractible level

- Compatibility across a wider range of drug formulations, including ethanol-containing formulations

- Suitable for all pMDI filling technologies

- Robust design for accurate and consistent performance

 

“Thanks to the introduction of our novel COCe within our DF30  Valve Technology Platform, Aptar Pharma is able to offer a series of key advantages to meet the evolving needs of our customers; including improved compatibility with both EtOH containing and dry drug formulations, superior cleanliness and improved leakage barrier characteristics which result in a more robust and less crimp sensitive manufacturing process,” said Chris Baron, Associate Director, Business Development, for Aptar Pharma.

 

For more information on DF30Plus, please click

:

 

http://www.aptar.com/pharma/prescription-division

 

                              

About Aptar Pharma

Aptar Pharma is a part of the AptarGroup family of companies, along with Aptar

Beauty + Home and Aptar Food + Beverage.

AptarGroup, Inc. is a leading global supplier of a broad range of innovative dispensing solutions for the beauty, personal care, home care, prescription drug, consumer health care, injectables, food, and beverage markets.

AptarGroup is headquartered in Crystal Lake, Illinois, with manufacturing facilities in North America, Europe, Asia and South America. To learn more, visit www.aptar.com/pharma.

 

Press Contacts

Elisa Eschylle, Events and Press Relations Manager

Tel.: + 33 (0)1 39 17 20 41 – Email: elisa.eschylle@aptar.com

Marion Baschet Vernet, Press Attaché

Tel.: + 33 (0)6 22 17 08 96 – Email: mbvernet@gmail.com

Related to this article

PharmTech Weekly Roundup—October 2, 2026
This week on PharmTech, Merck diversified its pipeline, USP emphasizes supply chain security, AI systems are examined, and speakers preview their presentations at CPHI Milan and AAPS PharmSci 360.
CPHI Milan 2026: Nitrosamine Risk Mitigation, Part 1
Capsugel's Bram Baert and Sandrine Picco argue that chasing zero nitrite in pharmaceutical excipients is often impractical and costly. They recommend setting scientifically justified, risk-based limits and consistently staying below them.
Regulatory Roundup—September 2026
The FDA opened an expedited IND pilot, tightened scrutiny of foreign trial data, and finalized a rule recognizing non-animal testing methods. In Europe, the EMA advanced pharmaceutical legislation reform, restricted 2 legacy products, and opened an injectable-iron safety review.