News|Articles|November 10, 2025
Confident identification of phase 1 metabolites using electron activated dissociation (EAD)
Author(s)SCIEX
Key Takeaways
This technical note describes the identification of pioglitazone phase 1 metabolites from a hepatocyte incubation using comprehensive spectral data from an orthogonal fragmentation technique. More informative MS/MS spectra provided by EAD aided in the software-based identification of phase 1 metabolites to support drug metabolism studies.
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