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ECDC and EMA have concluded that it is too early to consider using a fourth dose of mRNA COVID-19 vaccines in the general population.
The European Centre for Disease Prevention and Control (ECDC) and the European Medicine Agency’s (EMA’s) COVID-19 task force (ETC) have concluded that it is too early to consider using a fourth dose of mRNA COVID-19 vaccines in the general population. The vaccines being referred to are Pfizer’s Comirnaty and Moderna’s Spikevax.
ECDC and EMA concluded that there is currently no clear evidence in the European Union that adults with normal immune systems will benefit from a fourth dose. However, in adults aged 80 years and older, the agencies agreed that a fourth dose may be administered for the protection against COVID-19.
There may be a reevaluation of recommending a fourth dose for adults aged 60 to 79 years depending on the epidemiological situation changes and new data. As of now, there is no clear evidence that the current three-dose vaccination system is decreasing in effectiveness for this age group.
ECDC and EMA will continue to review available evidence on the effectiveness of COVID-19 vaccines and update their recommendations accordingly. National authorities in the EU make the final decisions on the administration of vaccines, including booster doses.