Poor solubility remains one of the most persistent and costly challenges in pharmaceutical drug development. Inside this eBook you'll find peer-reviewed research and expert perspectives on how AI, machine learning, and molecular dynamics simulations are transforming cyclodextrin-based drug formulation. From a novel nomenclature system that enables AI-driven structural optimization to a landmark case study examining remdesivir's interactions with sulfobutylether-β-cyclodextrins, readers will gain actionable insight into predictive modeling strategies that reduce API waste, accelerate development timelines, and improve the odds of getting complex small molecules to patients.
Onshoring pharmaceutical manufacturing can be made more practical by collaborating with CDMOs that have gray space, supported by strong relationships with used equipment dealers and OEMs.
Almac Clinical Services’ clinical supply strategy won the 2026 CPHI Award for Supply Chain Excellence. Nishma Patel, supply chain solutions manager, explains how her team managed the study’s strict −80 °C handling requirement, quality release, and site readiness, and how the Almac Adapt approach can apply beyond this program.
The FDA grants accelerated approval to subcutaneous amivantamab for head and neck cancer, extending the IV-to-subcutaneous shift in biologics formulation.
Almac Clinical Services’ clinical supply strategy won the 2026 CPHI Award for Supply Chain Excellence. Nishma Patel, supply chain solutions manager, explains the benefits and challenges of the company’s just-in-time manufacturing solution.
Vivek Gupta of Duquesne University explains at AAPS PharmSci 360 why device decisions can't wait and why excipient makers must test beyond drug molecules.
