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Pharmaceutical Technology

Pharmaceutical Technology-10-02-2015
Volume38
Issue 10
Pages: 14

Microfluidics Systems Designed for Flow-Chemistry Experiments

The flexible Dolomite Flow Chemistry Systems from Dolomite Microfluidics can be configured to suit different applications.

The flexible Dolomite Flow Chemistry Systems from Dolomite Microfluidics can be configured to suit different applications. The systems can be used in education, continuous large-scale reactions, process optimization, scale-up, and multi-step reactions.

The Dolomite Flow Chemistry Systems are designed to provide control of residence time, reaction temperature, stoichiometry, and reagent introduction for performing detailed flow-chemistry experiments. The systems include a choice of glass microreactors or tube reactors in polytetrafluoroethylene or stainless steel from 2.5 µl up to 16 mL. The TCU-125 Temperature Controller ensures accurate temperature control of chips from 1 to 125 °C, and the tube reactors can be heated from room temperatures to 250 °C using a hotplate. The high performance and robust Mitos Duo syringe pumps ensure smooth flow rates, from 1.0 µl/min to 10 mL/min, and allow use of the two syringes independently or in one continuous flow, up to 6 bar. Standard systems can be upgraded for additional functionality, such as reaction automation, continuous work-up, small volume sample injection, or pressurized inputs. 

Dolomite Microfluidicswww.dolomite-microfluidics.com
 

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