Univar Solutions scientists developed a lidocaine cream built on starch, sorbitol, coconut oil, and beeswax that matched a commercial benchmark on viscosity, assay, and hydration.
News|Articles|April 2, 2019
- Pharmaceutical Technology-04-02-2019
- Volume 43
- Issue 4
New MALS Detector
Tosoh Bioscience’s LenS3 Multi-Angle Light Scattering (MALS) detector offers a new approach for measuring molecular weight (MW) and radius of gyration (Rg) of synthetic polymers, polysaccharides, proteins, and biopolymers.
Tosoh Bioscience’s LenS3Multi-Angle Light Scattering (MALS) detector offers a new approach for measuring molecular weight (MW) and radius of gyration (Rg) of synthetic polymers, polysaccharides, proteins, and biopolymers. The new detector has a new optical design, cell-block assembly, and calculation methodology. Featuring a patent-pending cell geometry and a lower wavelength laser (at 514 nm), the detector allows direct measurement of MW and provides high sensitivity. Additionally, with an improved normalization process and a new method for using the angular dependence, the determination of radius of gyration of smaller macromolecules below 10 nm in gyration size Rgis now possible, according to the company.
The instrument is supported by SECview software, which streamlines the calculations required by the advanced detectors and performs analysis of sample-of-interest using multiple calibration methods simultaneously. The software is capable of gel permeation chromatography system/hardware control, multi-channel data acquisition, data processing, and analysis.
Articles in this issue
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Cleaning Chromatography Resin Residues from Surfacesover 7 years ago
OSD Continuous Manufacturing Strategiesover 7 years ago
Channeling Customer Complaints into Qualityover 7 years ago
Continuous Manufacturing Gains Major Push from FDAover 7 years ago
Particles on Best Behaviorover 7 years ago
Spray Drying: Supporting Patient-Centric Drug Developmentover 7 years ago
Advanced Cell Penetrating Peptide Systems for Gene Therapyover 7 years ago
Degradation Pathways: A Case Study with Pegylated L-Asparaginaseover 7 years ago
Locking Fraudulent Materials Out of the Supply ChainRelated to this article
Nate Edwards of Arya Consulting moderates a discussion with Elisabeth Gardiner of Tevard Biosciences and Donny Xu of the RTW Institute about the regulatory and manufacturing hurdles facing rare disease drug developers.
FDA grants ravulizumab accelerated approval in IgA nephropathy after a 43.4% proteinuria cut, signaling new IV biologic demand for drug manufacturers.
Jane Zhang of ETCH Sourcing explains why geopolitics, transparency, and partnership now weigh as heavily as cost and quality when companies choose suppliers, in this episode of Ask the Expert, moderated by Susan J. Schniepp of Nelson Labs.
FDA approves GSK's bepirovirsen for chronic hepatitis B after a 19% functional cure rate, raising oligonucleotide scale-up stakes for manufacturers.
Ravi Kiran Kaja, PhD, USP, explains what harmonization of extractables and leachables standards looks like in practice.
Jaenisch, Muraru, and Pandey discuss new skills for QC and regulatory teams, plus patient trust, as new approach methodologies reshape pharma.
Nine duloxetine recalls since 2024 show why generic drug manufacturers need route-level nitrosamine risk assessment, not end-product testing alone.
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