New MALS Detector

Tosoh Bioscience’s LenS₃Multi-Angle Light Scattering (MALS) detector offers a new approach for measuring molecular weight (MW) and radius of gyration (R_g) of synthetic polymers, polysaccharides, proteins, and biopolymers. The new detector has a new optical design, cell-block assembly, and calculation methodology. Featuring a patent-pending cell geometry and a lower wavelength laser (at 514 nm), the detector allows direct measurement of MW and provides high sensitivity. Additionally, with an improved normalization process and a new method for using the angular dependence, the determination of radius of gyration of smaller macromolecules below 10 nm in gyration size R_gis now possible, according to the company.

The instrument is supported by SECview software, which streamlines the calculations required by the advanced detectors and performs analysis of sample-of-interest using multiple calibration methods simultaneously. The software is capable of gel permeation chromatography system/hardware control, multi-channel data acquisition, data processing, and analysis.

Tosoh Bioscience