News

Article

Pharmaceutical Technology's In the Lab eNewsletter

In the Lab eNewsletter

Pharmaceutical Technology\'s In the Lab eNewsletter-02-05-2020
Volume15
Issue 2

Otsuka, PhoreMost Team Up for Drug Discovery

Otsuka will use PhoreMost’s phenotypic screening platform to identify new targets for drug development, with a focus on gene therapy.

On January 21, 2020, Otsuka Pharmaceutical and PhoreMost, a Cambridge, UK-based biopharmaceutical company, entered into a multi-project drug discovery collaboration that will pursue both small molecule therapeutics as well as gene therapy applications.

PhoreMost will contribute its in-house expertise and phenotypic screening platform, Siteseeker, to evaluate disease-relevant pathways nominated by Otsuka, which will further characterize and validate novel targets that have been identified. The partners will initially focus on gene therapy applications, according to a company press release.

PhoreMost’s platform, which is based on Proteini, a proprietary protein interference technology, exploits protein shape diversity to find functionally active peptides. This approach can significantly enhance the power of phenotypic screening and translation into therapeutic modalities, company executives claim. PhoreMost uses Siteseeker to probe the entire proteome in a live cell environment to identify novel druggable targets linked to any chosen disease. This enables the systematic discovery of the functionally active peptides that are directly linked to useful therapeutic applications, according to PhoreMost.

Source: PhoreMost

Newsletter

Get the essential updates shaping the future of pharma manufacturing and compliance—subscribe today to Pharmaceutical Technology and never miss a breakthrough.

Related Videos
A global supply chain map, visualizing the complex network of transportation routes and distribution centers | Image Credit: © venusvi - stock.adobe.com
Shortcut from point A to point B | Image Credit: © Olivier Le Moal - stock.adobe.com
Behind the Headlines, Episode 21: Waters-BD Merger, Merck’s $10B Bet, and Biotech’s Investment Frontiers
Wooden blocks spelling TARIFFS are placed on a map of North America, specifically over the United States and Mexico | Image Credit: © Rokas - stock.adobe.com
Jason Waite, International Trade Expert, Alston & Bird
Simona Guidi, Associate Director, ProPharma
Tore Bergsteiner
Behind the Headlines, Episode 20: CAR-T Milestones, Abbvie and Eli Lilly M&A Moves, and More
Related Content