Protein Analyzer Offers Ability to Measure Protein Titer Directly from Bioreactor

Published on: 

Pharmaceutical Technology's In the Lab eNewsletter

In the Lab eNewsletter, Pharmaceutical Technology\'s In the Lab eNewsletter-09-04-2019, Volume 14, Issue 9

The Tridex Protein Analyzer from IDEX offers the ability to directly measure protein titer from a bioreactor in real time.

The Tridex Protein Analyzer from IDEX Health & Science offers the ability to directly measure protein titer from a bioreactor in real time. The analyzer is a compact and an easy-to-use solution for at-line titer monitoring in a bioprocess environment. It is built to ensure that at-line results directly correlate to offline high-performance liquid chromatography methodology.

The biopharma industry has long been seeking an alternative to time-consuming offline methods currently in use, and the measurement of antibody titer is a critical parameter for manufacturing biologics and biosimilars, the company reports. The Tridex Analyzer quickly delivers accurate titer measurements over a dynamic range of 0.1–10 g/L, with minimal sample manipulation for use in R&D and process development.

The Tridex Analyzer is the first protein analyzer on the market built specifically for bioprocess monitoring, according to the company. It uses a unique trap and elute technique to accurately monitor the titer in a bioreactor. It does not require chromatography expertise, specialized training, or extensive method development. The sample flowpath is completely enclosed, lending itself to the requirements of single-use bioprocessing.


The Tridex system also offers the option to connect to an automated sampling system for complete integration into a bioprocessing environment and to deliver actionable results with just a few clicks. IDEX launched the new analyzer in July 2019.

Source: IDEX Health & Science